PREDICTORS FOR INPATIENT MORTALITY AMONG HOSPITALIZATIONS WITH VENTILATOR-ASSOCIATED PNEUMONIA: NATIONAL INPATIENT DATABASE 2016-2017

TOPIC: Chest Infections TYPE: Original Investigations PURPOSE: Ventilator-associated pneumonia (VAP) is a major cause of healthcare-associated mortality and morbidity in critically ill patients who are mechanically ventilated. The purpose this study to describe the various primary discharge diagnoses hospitalizations with ventilator-associated pneumonia, identify their demographic characteristics, risk factors for pneumonia. METHODS: Hospitalizations diagnosis were ventilated over twenty-four hours selected from National Inpatient Sample 2016 2017. top fifteen principal proportions among VAP identified. Independent predictors inpatient ventilator associated Confounders adjusted using multivariate regression analysis. RESULTS: In total, 33,140 analyzed. leading sepsis due unspecified organism (16.92%), respiratory failure (8.09%), (6.38%). Mortality was 20.9%. uninsured status (aOR 2.13, 95% CI 1.49 – 3.06, p<0.001), acute renal 2.00, 1.75 2.30, liver disease 1.82, 1.52 2.18, p<0.001). CONCLUSIONS: significant mortality. Infective, traumatic, cardiovascular, conditions accounted 85% VAP. Acute failure, presence disease, lack insurance greater CLINICAL IMPLICATIONS: recognized as secondary impaired muco-ciliary clearance airways micro-aspirations around endotracheal tube cuff. Although there literature discussing pathophysiology healthcare burden VAP, need objective data focusing on in-hospital diagnosed This retrospective cohort designed address paucity literature. We aimed establish investigate associations between numerous study, we found that or likelihood Thus, strongly believe those hospitalized may be at higher death should monitored appropriately but aggressively. Ultimately, any patient potentially developing pneumonia; therefore, understanding risks an important measure improving survival patients. DISCLOSURES: No relevant relationships by Zain El-amir, source=Web Response Asim Kichloo, Hafeez Shaka, Farah Wani, Timothy Schwarz,